Biochemical, histopathological and morphological alterations in the kidneys of wistar rats following exposure to X-ray film developer solutions

Radiographers and darkroom staff in developing countries engaged in darkroom radiography are often exposed to x-ray film processing chemicals including the developer. The possible effects of the developer have not been investigated to the best of our knowledge. This study was aimed at investigating the effects of x-ray film developer on the kidneys of wistar […]

Knowledge, attitude and practice of haemovigilance among healthcare professionals in a Nigerian Tertiary Hospital

protocols in health facility is essential to the attainment of universal blood transfusion safety. Objective The objective of the article was to determine the knowledge, attitude and practice of haemovigilance by healthcare professionals in a Nigerian Hospital. Patients and methods This was a cross-sectional study; an anonymous structured questionnaire was used. In all, 270 consenting […]

EFFECT OF ANTIRETROVIRAL DRUG THERAPY ON IRON STATUS, URIC ACID, CD4+T-CELLS AND WEIGHT OF HIV SEROPOSITIVE SUBJECTS

Background: Human immunodeficiency virus (HIV) /Acquired immunodeficiency syndrome (AIDS) is one of the pandemic infections that ravage humans. HIV/AIDS diseases progress with decrease in weight, CD4+T cells count is lowered resulting to the production of uric acid which chelates the available iron leading to anemia. The use of antiretroviral agents further complicates the biochemical changes […]

EFFECT OF ANTIRETROVIRAL DRUG THERAPY ON IRON STATUS, URIC ACID, CD4+T-CELLS AND WEIGHT OF HIV SEROPOSITIVE SUBJECTS

Background: Human immunodeficiency virus (HIV) /Acquired immunodeficiency syndrome (AIDS) is one of the pandemic infections that ravage humans. HIV/AIDS diseases progress with decrease in weight, CD4+T cells count is lowered resulting to the production of uric acid which chelates the available iron leading to anemia. The use of antiretroviral agents further complicates the biochemical changes […]

Serum micronutrient levels and disease severity score in patients with sickle cell anaemia

Background Disease severity in patients with sickle cell anaemia (SCA) is accentuated by the risk for infection, which could potentially be influenced by serum levels of micronutrients, particularly those that are components of the antioxidant system of the body. Objective The aim of this study was to evaluate serum levels of the micronutrients zinc, copper, […]

Genital tract microbial isolate in women with preterm pre-labour rupture of membranes in resource-constrained community setting

This study determined patterns of microbial isolates in genital tract of women with preterm pre-labour rupture of membranes (PPROM) compared with cases without PPROM. Endocervical swabs of women with confi rmed diagnosis of PPROM were examined microbiologically and compared in blinded pattern with gestational-age-matched controls. One hundred and fi ve microbiological results each for cases […]

Effect of Chloroquine on the Urinary Excretion of Ciprofloxacin

Ciprofloxacin is an inexpensive antibacterial, whereas chloroquine is an inexpensive antimalarial. The coadministration of chloroquine and ciprofloxacin is easily encountered because both drugs are commonly prescribed to patients in the tropics. Five healthy male volunteers aged 19 to 31 years who were not taking any of the prescribed medications and who had no sensitivity to […]

Assessment of Lipid Profile in HIV Seropositive Pregnant Women attending Ante-Natal Clinic in Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria

Undesirable changes in lipid metabolism have been reported among HIV-infected individuals undergoing anti-retroviral therapy. Considering the peculiarity of pregnant women who are also faced with similar metabolic changes, it becomes necessary to ascertain lipid changes that occur in them, and assess the effect of anti-retroviral therapy (ART), diet and physical exercise on their lipid profile.